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MELANOTAN II

Buy Melanotan II UK

20mg per vial — UK-supplied, COA per batch, in-vitro research use only.

Melanotan II (MT-II) is a cyclic α-MSH analogue used as a broad-spectrum melanocortin-receptor reference agonist in laboratory research. UK-supplied at 20mg per vial. Supplied strictly for in-vitro research use — not a licensed medicine, and not for human or veterinary use.

Our research-supply standards

99%+ HPLC Purity

Every batch is verified by high-performance liquid chromatography. The measured purity figure is recorded on the batch COA — not a marketing claim.

COA With Every Order

A batch-specific Certificate of Analysis ships with every order. Sample COAs are accessible from the COA library before you order.

UK Dispatch

Orders confirmed before the daily cut-off ship the same working day from our UK facility, with tracked next-working-day UK delivery as standard.

Research-Only Supply

All compounds are supplied strictly for in-vitro laboratory research. Documentation, labelling and packaging reflect that restriction.

Melanotan II

Melanotan II

Melanotan II | 20mg | 3ml

£100.00

Free reusable pen included

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Melanotan II supplied as a laboratory reference compound, with a batch COA

Melanotan II is supplied here strictly as a melanocortin reference standard for in-vitro laboratory research. It is not a licensed medicine in the UK, it is not supplied for human or veterinary use, and no therapeutic or cosmetic claim is made for it anywhere on this site. Within that framing, what a research buyer needs is documentation and consistent handling: every order ships with a batch-specific Certificate of Analysis recording the measured purity and identity data for that production lot, with recent certificates published in our on-site COA library. Vials are handled cold-chain through to dispatch and ship as pre-mixed solutions. Orders confirmed before the daily cut-off leave a UK facility the same working day on tracked next-working-day delivery. Larger or recurring requirements are handled through our trade desk.

What Melanotan II is studied for in the research literature

Melanotan II (MT-II) is a synthetic cyclic heptapeptide analogue of α-melanocyte-stimulating hormone (α-MSH), developed for controlled laboratory investigation of the melanocortin signalling system. Its sequence — Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂ — incorporates a norleucine substitution, a D-phenylalanine substitution and a lactam bridge that cyclises the molecule. Together these confer markedly greater stability and resistance to enzymatic degradation than the native linear hormone, which is what makes it a workable reference compound under laboratory conditions.

In biochemical and cellular systems MT-II acts as a broad, non-selective agonist across the melanocortin receptor family — MC1R, MC3R, MC4R and MC5R — with negligible activity at MC2R. That wide receptor coverage is precisely why it functions as a foundational tool: it provides the unselective baseline against which more receptor-selective analogues are characterised, in work on melanocortin-receptor binding, G-protein-coupled cAMP signalling and downstream transcriptional responses. Reported responses vary with receptor subtype, concentration, exposure time, cell model and study design.

Nothing on this page describes dosing, administration, reconstitution for use, or any application in humans or animals, and no therapeutic claim is made.

Regulatory position and how this material is supplied

The position in the UK is unambiguous and worth stating plainly. The MHRA has repeatedly warned that products containing Melanotan sold for human use — typically marketed for tanning — are unlicensed, are unlawful to supply for that purpose, and are of unknown safety and quality when obtained through those channels. It has acted against suppliers marketing them that way. Melanotan II holds no UK marketing authorisation.

Material supplied here sits outside that entirely: it is sold as a laboratory reference compound for in-vitro research, labelled for that use, and documented accordingly. Purchasers must be 18 or over, must be acquiring it for genuine laboratory research, and must not use it in humans or animals. If you are looking for a product for personal or cosmetic use, this is not one, and we will not supply it on that basis.

For researchers who need the receptor-selective comparator rather than the broad-spectrum agonist, [PT-141](/buy-pt-141-uk) is the closely related MC4R-selective analogue, and we supply both with matching documentation.

Frequently asked questions

What is Melanotan II?
A synthetic cyclic heptapeptide analogue of α-melanocyte-stimulating hormone, stabilised by a lactam bridge, used in laboratory research on melanocortin-receptor pharmacology.
What strength do you supply?
20mg per vial. The batch COA documents the recorded purity and identity data for that lot.
Why is Melanotan II studied?
It is a broad, non-selective agonist across MC1R, MC3R, MC4R and MC5R, which makes it a foundational reference point in receptor-selectivity and structure–activity research.
What is the UK regulatory position?
The MHRA has warned that Melanotan products sold for human use are unlicensed and unlawful to supply for that purpose. Melanotan II is not a licensed medicine in the UK. Material here is supplied strictly as a laboratory reference compound for in-vitro use.
How does it compare with PT-141?
PT-141 shares the scaffold but carries a free acid at the C-terminus rather than an amide, shifting it toward MC4R selectivity. Melanotan II remains the broad-spectrum comparator.

Order research compounds from a UK supplier

Browse the full catalogue, view the COA library for a recent batch, or open a trade account for institutional supply. All orders dispatch from our UK facility with HPLC-verified compounds.

Melanotan II is supplied strictly as a reference compound for in-vitro laboratory research. It is not a licensed medicine in the UK, holds no marketing authorisation, and is not supplied for human or veterinary use, tanning, or any cosmetic purpose. The MHRA has warned that Melanotan products sold for human use are unlicensed and unlawful to supply for that purpose. No therapeutic, cosmetic or physiological claim is made for this material.

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