NAD+ is an essential coenzyme found in every living cell. Its primary functions are critical for maintaining cellular health and life:

Energy Production

It is crucial for the process of converting nutrients into cellular energy (ATP), particularly in the mitochondria (the cell's "powerhouses").

DNA Repair

NAD+ is consumed by enzymes like PARPs (poly-ADP-ribose polymerases), which are vital for repairing damaged DNA and maintaining genomic stability.

Cellular Signaling

It serves as fuel for sirtuins, often called "longevity proteins." Sirtuins regulate various aspects of cellular health, stress resistance, and healthy aging.

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NAD+ and Aging

NAD+ levels naturally decline with age, potentially dropping by as much as 50%. This decline is associated with several common signs and symptoms of aging:

Fatigue and Low Energy

Slower Recovery from exercise or illness

Poor Sleep Quality

Visible Signs of Aging

Restoring these levels, often through methods like the injections you mentioned, is suggested to help boost energy, support recovery, and promote cellular rejuvenation by fueling the critical processes that NAD+ facilitates.

3 Reasons NAD+ Declines

Senescent Cells

Aging cells that stop dividing but don't die, accumulating over time and consuming NAD+ while releasing harmful substances.
CD-38 Enzymes

Enzymes that break down NAD+ molecules, increasing in activity with age and chronic inflammation.
Chronic Inflammation

Persistent low-level inflammation that accelerates NAD+ depletion and activates NAD+-consuming enzymes.